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Orion Research Solutions

MOTS-c 10mg

10 mg

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Longevity & Wellness

MOTS-c 10mg

MOQ 10 units

MOTS-c is a mitochondrial-derived peptide encoded in mitochondrial DNA, studied for AMPK activation and metabolic homeostasis. Research applications include insulin sensitivity models, mitochondrial-nuclear signaling, and exercise-associated metabolic investigation. As one of very few characterized mitochondrial-derived peptides, it gives laboratories a direct experimental handle on retrograde mitochondrial-to-nuclear communication in metabolic research.

Volume pricing

$64.00per unit

Pricing for your account: Standard Wholesale

Minimum 10 units

Volume pricing is based on the quantity ordered per product. Minimum order quantity: 10 units per product.

Research Overview

MOTS-c is a 16-amino-acid peptide encoded within the mitochondrial 12S rRNA gene, making it a member of the small class of mitochondrial-derived peptides — molecules that originate in the mitochondrial genome yet act as regulatory signals in the cytosol and nucleus. The published literature describes activation of AMP-activated protein kinase, influence on the folate-methionine cycle and purine biosynthesis, and translocation to the nucleus under metabolic stress where it is reported to regulate adaptive gene expression. This positions MOTS-c as a mediator of retrograde mitochondrial-to-nuclear communication, a concept of substantial interest in metabolic and ageing research. Laboratory applications include AMPK phosphorylation assays, glucose uptake studies in myotubes, insulin sensitivity models, nuclear translocation imaging, and exercise-metabolism protocols.

Common Research Areas

  • Mitochondrial-derived peptide research
  • AMPK signaling
  • Insulin sensitivity models
  • Metabolic homeostasis
  • Mitochondrial-nuclear communication
  • Exercise metabolism studies

Key Features

  • Presentation: Lyophilized vial at 10 mg
  • Category: Longevity & Wellness — wholesale supply only
  • Minimum order quantity: 10 units per SKU
  • Applied in mitochondrial-derived peptide research and ampk signaling
  • Cold-chain handling: store at 2–8°C, protected from light
  • Research Use Only — not for human or animal consumption

Product Information

Category
Longevity & Wellness
Format
Lyophilized vial
Strength
10 mg
Minimum Order Quantity
10 units
Wholesale Availability
Wholesale only

Why Researchers Choose This Product

MOTS-c is one of very few characterized mitochondrial-derived peptides, giving laboratories a direct experimental handle on retrograde mitochondrial signaling. Its AMPK-linked mechanism connects cleanly to established metabolic assays, making it straightforward to integrate into existing protocols.

Storage

Store lyophilized vials refrigerated at 2–8°C. Protect from heat and light. Reconstituted material should be kept refrigerated and handled under aseptic laboratory conditions. For laboratory research use only.

Frequently Asked Questions

What is MOTS-c 10mg studied for?
MOTS-c is a mitochondrial-derived peptide encoded in mitochondrial DNA, studied for AMPK activation and metabolic homeostasis. Research applications include insulin sensitivity models, mitochondrial-nuclear signaling, and exercise-associated metabolic investigation. As one of very few characterized mitochondrial-derived peptides, it gives laboratories a direct experimental handle on retrograde mitochondrial-to-nuclear communication in metabolic research.
What research applications does MOTS-c 10mg support?
Reported laboratory applications span mitochondrial-derived peptide research, ampk signaling, insulin sensitivity models, metabolic homeostasis, mitochondrial-nuclear communication, and exercise metabolism studies. MOTS-c is one of very few characterized mitochondrial-derived peptides, giving laboratories a direct experimental handle on retrograde mitochondrial signaling. Its AMPK-linked mechanism connects cleanly to established metabolic assays, making it straightforward to integrate into existing protocols.
What format, strength, and minimum order apply?
MOTS-c 10mg is supplied as lyophilized vial at 10 mg. The minimum order quantity is 10 units per SKU, and it is available to wholesale buyers only — laboratories, research organizations, distributors, and qualified commercial accounts.
How should this product be stored and handled?
Store lyophilized vials refrigerated at 2–8°C. Protect from heat and light. Reconstituted material should be kept refrigerated and handled under aseptic laboratory conditions. For laboratory research use only.
Is this product suitable for human or animal use?
No. This product is supplied strictly for laboratory and scientific research by qualified professionals. It is not for human or animal consumption, is not intended for human or veterinary use, and is not approved to diagnose, treat, cure, or prevent any disease.

Important Notice

Research Use Only. Not for human or animal consumption. These products are intended exclusively for laboratory and scientific research by qualified professionals. They are not intended for human or veterinary use and are not approved to diagnose, treat, cure, or prevent any disease.

This product is intended exclusively for laboratory research and analytical purposes. NOT FOR HUMAN CONSUMPTION. Not intended to diagnose, treat, cure, or prevent any disease.