BAM-15 50mg/ SLU-PP-332 50mg

Research Overview

BAM-15 is a mitochondrial protonophore that dissipates the inner membrane proton gradient, uncoupling oxidative phosphorylation from ATP synthesis and increasing substrate oxidation. It is distinguished in the literature from classical uncouplers by a reported wider margin between effective and cytotoxic concentrations, and by activity that does not depolarize the plasma membrane. SLU-PP-332 operates through an entirely different mechanism as an agonist of estrogen-related receptors, nuclear transcription factors that govern mitochondrial biogenesis and oxidative gene programs — a pathway associated in preclinical work with exercise-mimetic transcriptional signatures. Combining an acute bioenergetic intervention with a transcriptional one allows investigators to probe whether immediate uncoupling and longer-term biogenesis interact. Laboratory applications include oxygen consumption rate measurement, mitochondrial membrane potential assays, ERR transactivation studies, and myotube gene-expression profiling.

Common Research Areas

• Mitochondrial bioenergetics
• Oxidative phosphorylation studies
• Nuclear receptor signaling
• Mitochondrial biogenesis
• Metabolic research
• Exercise physiology models

Key Features

• Presentation: Lyophilized vial (blend) at BAM-15 50 mg / SLU-PP-332 50 mg
• Category: Longevity & Wellness — wholesale supply only
• Minimum order quantity: 10 units per SKU
• Applied in mitochondrial bioenergetics and oxidative phosphorylation studies
• Cold-chain handling: store at 2–8°C, protected from light
• Research Use Only — not for human or animal consumption

Product Information

Category

Longevity & Wellness

Format

Lyophilized vial (blend)

Strength

BAM-15 50 mg / SLU-PP-332 50 mg

Minimum Order Quantity

10 units

Wholesale Availability

Wholesale only

Why Researchers Choose This Product

Pairing an uncoupler with a transcriptional agonist gives laboratories access to both acute and adaptive arms of mitochondrial metabolism in one formulation. This is valuable in seahorse-style respirometry programs where bioenergetic and gene-expression endpoints are measured in parallel.

Storage

Store lyophilized vials refrigerated at 2–8°C. Protect from heat and light. Reconstituted material should be kept refrigerated and handled under aseptic laboratory conditions. For laboratory research use only.

Frequently Asked Questions

What is BAM-15 50mg/ SLU-PP-332 50mg studied for?

This blend pairs BAM-15, a mitochondrial uncoupler, with SLU-PP-332, an estrogen-related receptor agonist. Together they engage bioenergetic and transcriptional arms of metabolism, supporting research into mitochondrial efficiency and exercise-associated gene programs. Pairing an acute bioenergetic intervention with a transcriptional one lets investigators probe whether immediate uncoupling and longer-term mitochondrial biogenesis interact in metabolic models.

What research applications does BAM-15 50mg/ SLU-PP-332 50mg support?

Reported laboratory applications span mitochondrial bioenergetics, oxidative phosphorylation studies, nuclear receptor signaling, mitochondrial biogenesis, metabolic research, and exercise physiology models. Pairing an uncoupler with a transcriptional agonist gives laboratories access to both acute and adaptive arms of mitochondrial metabolism in one formulation. This is valuable in seahorse-style respirometry programs where bioenergetic and gene-expression endpoints are measured in parallel.

What format, strength, and minimum order apply?

BAM-15 50mg/ SLU-PP-332 50mg is supplied as lyophilized vial (blend) at BAM-15 50 mg / SLU-PP-332 50 mg. The minimum order quantity is 10 units per SKU, and it is available to wholesale buyers only — laboratories, research organizations, distributors, and qualified commercial accounts.

How should this product be stored and handled?

Store lyophilized vials refrigerated at 2–8°C. Protect from heat and light. Reconstituted material should be kept refrigerated and handled under aseptic laboratory conditions. For laboratory research use only.

Is this product suitable for human or animal use?

No. This product is supplied strictly for laboratory and scientific research by qualified professionals. It is not for human or animal consumption, is not intended for human or veterinary use, and is not approved to diagnose, treat, cure, or prevent any disease.

This product is intended exclusively for laboratory research and analytical purposes. NOT FOR HUMAN CONSUMPTION. Not intended to diagnose, treat, cure, or prevent any disease.