Sermorelin is a synthetic 29-amino-acid analogue of human growth hormone-releasing hormone (GHRH). It is designed to interact with GHRH receptors and has been studied for its role in stimulating endogenous growth hormone secretion and related endocrine signaling pathways.

Research involving sermorelin has focused on the regulation of growth hormone release, pituitary signaling, and downstream hormonal pathways. Its defined peptide structure makes it a useful compound for laboratory investigation of GHRH-mediated biological processes.

Sermorelin acetate has also been associated with the former prescription product Geref and has an FDA history involving growth hormone deficiency in children. Research-grade sermorelin should therefore not be represented as an approved medicine or as a substitute for regulated pharmaceutical products.