TB 500 5mg

Research Overview

TB-500 represents the actin-binding domain of thymosin beta-4, a naturally occurring protein and one of the most abundant peptides in mammalian cells. Its principal characterized mechanism is sequestration of monomeric G-actin, which regulates the pool available for filament polymerization and thereby influences cytoskeletal remodeling. Because cell migration, differentiation, and morphological change all depend on controlled actin dynamics, this activity connects to a broad set of biological processes. The preclinical literature describes effects on endothelial and epithelial cell migration, angiogenic sprouting, and remodeling in cardiac and dermal injury models, alongside reported anti-inflammatory activity. Laboratory applications include actin polymerization assays, scratch and transwell migration studies, endothelial sprouting models, cardiac repair research, and combination studies with angiogenic peptides.

Common Research Areas

• Cytoskeletal dynamics
• Cell migration assays
• Tissue repair research
• Cardiovascular research models
• Angiogenesis signaling
• Actin polymerization studies

Key Features

• Presentation: Lyophilized vial at 5 mg
• Category: Recovery & Healing — wholesale supply only
• Minimum order quantity: 10 units per SKU
• Applied in cytoskeletal dynamics and cell migration assays
• Cold-chain handling: store at 2–8°C, protected from light
• Research Use Only — not for human or animal consumption

Product Information

Category

Recovery & Healing

Format

Lyophilized vial

Strength

5 mg

Minimum Order Quantity

10 units

Wholesale Availability

Wholesale only

Why Researchers Choose This Product

TB-500 provides a direct handle on actin dynamics, a mechanism distinct from growth-factor-driven repair signaling. Laboratories frequently pair it with angiogenic peptides precisely because the pathways do not overlap, allowing additive effects to be tested cleanly.

Storage

Store lyophilized vials refrigerated at 2–8°C. Protect from heat and light. Reconstituted material should be kept refrigerated and handled under aseptic laboratory conditions. For laboratory research use only.

Frequently Asked Questions

What is TB 500 5mg studied for?

TB-500 is a synthetic peptide corresponding to the active region of thymosin beta-4, studied for actin binding and cytoskeletal regulation. Research applications include cell migration, tissue repair, and cardiovascular models examining motility-dependent processes. Its actin-binding mechanism is distinct from growth-factor-driven repair signaling, making it a natural pairing partner for angiogenic peptides in combination studies.

What research applications does TB 500 5mg support?

Reported laboratory applications span cytoskeletal dynamics, cell migration assays, tissue repair research, cardiovascular research models, angiogenesis signaling, and actin polymerization studies. TB-500 provides a direct handle on actin dynamics, a mechanism distinct from growth-factor-driven repair signaling. Laboratories frequently pair it with angiogenic peptides precisely because the pathways do not overlap, allowing additive effects to be tested cleanly.

What format, strength, and minimum order apply?

TB 500 5mg is supplied as lyophilized vial at 5 mg. The minimum order quantity is 10 units per SKU, and it is available to wholesale buyers only — laboratories, research organizations, distributors, and qualified commercial accounts.

How should this product be stored and handled?

Store lyophilized vials refrigerated at 2–8°C. Protect from heat and light. Reconstituted material should be kept refrigerated and handled under aseptic laboratory conditions. For laboratory research use only.

Is this product suitable for human or animal use?

No. This product is supplied strictly for laboratory and scientific research by qualified professionals. It is not for human or animal consumption, is not intended for human or veterinary use, and is not approved to diagnose, treat, cure, or prevent any disease.

This product is intended exclusively for laboratory research and analytical purposes. NOT FOR HUMAN CONSUMPTION. Not intended to diagnose, treat, cure, or prevent any disease.