IGF1-Lr3 1mg

Research Overview

IGF-1 LR3 (Long R3 IGF-1) is a recombinant analog of insulin-like growth factor 1 modified in two ways: substitution of arginine at position 3 and addition of a 13-amino-acid N-terminal extension. Together these substantially reduce affinity for the IGF binding proteins that normally sequester circulating IGF-1, leaving a greater fraction of the molecule free to engage the IGF-1 receptor and markedly extending functional activity. This property is precisely why the analog is a mainstay of cell culture: in vitro systems contain binding proteins secreted by cultured cells that would otherwise sequester native IGF-1 unpredictably, confounding dose-response relationships. Laboratory applications include serum-free media supplementation, proliferation and differentiation assays, IGF-1R and PI3K/Akt signaling studies, myoblast culture, and bioprocess cell expansion.

Common Research Areas

• IGF-1 receptor signaling
• Cell proliferation assays
• Cell culture supplementation
• PI3K/Akt pathway research
• Myoblast and muscle cell studies
• Growth factor pharmacology

Key Features

• Presentation: Lyophilized vial at 1 mg
• Category: Growth Hormone & Performance — wholesale supply only
• Minimum order quantity: 10 units per SKU
• Applied in igf-1 receptor signaling and cell proliferation assays
• Cold-chain handling: store at 2–8°C, protected from light
• Research Use Only — not for human or animal consumption

Product Information

Category

Growth Hormone & Performance

Format

Lyophilized vial

Strength

1 mg

Minimum Order Quantity

10 units

Wholesale Availability

Wholesale only

Why Researchers Choose This Product

Reduced binding-protein affinity is what makes IGF-1 LR3 the standard growth factor for cell culture work — native IGF-1 is sequestered unpredictably by binding proteins in culture media, corrupting dose-response data. The analog delivers reproducible receptor engagement.

Storage

Store lyophilized vials refrigerated at 2–8°C. Protect from heat and light. Reconstituted material should be kept refrigerated and handled under aseptic laboratory conditions. For laboratory research use only.

Frequently Asked Questions

What is IGF1-Lr3 1mg studied for?

IGF-1 LR3 is a modified analog of insulin-like growth factor 1 engineered for reduced binding-protein affinity and extended activity. It is widely used in cell culture research on proliferation, differentiation, and IGF-1 receptor signaling. Reduced binding-protein affinity is what makes it the standard growth factor for cell culture, where native IGF-1 would be sequestered unpredictably by secreted binding proteins.

What research applications does IGF1-Lr3 1mg support?

Reported laboratory applications span igf-1 receptor signaling, cell proliferation assays, cell culture supplementation, pi3k/akt pathway research, myoblast and muscle cell studies, and growth factor pharmacology. Reduced binding-protein affinity is what makes IGF-1 LR3 the standard growth factor for cell culture work — native IGF-1 is sequestered unpredictably by binding proteins in culture media, corrupting dose-response data. The analog delivers reproducible receptor engagement.

What format, strength, and minimum order apply?

IGF1-Lr3 1mg is supplied as lyophilized vial at 1 mg. The minimum order quantity is 10 units per SKU, and it is available to wholesale buyers only — laboratories, research organizations, distributors, and qualified commercial accounts.

How should this product be stored and handled?

Store lyophilized vials refrigerated at 2–8°C. Protect from heat and light. Reconstituted material should be kept refrigerated and handled under aseptic laboratory conditions. For laboratory research use only.

Is this product suitable for human or animal use?

No. This product is supplied strictly for laboratory and scientific research by qualified professionals. It is not for human or animal consumption, is not intended for human or veterinary use, and is not approved to diagnose, treat, cure, or prevent any disease.

This product is intended exclusively for laboratory research and analytical purposes. NOT FOR HUMAN CONSUMPTION. Not intended to diagnose, treat, cure, or prevent any disease.