CJC-1295 with DAC 5mg

Research Overview

CJC-1295 with DAC is a modified GHRH(1-29) analog carrying a maleimidoproprionic acid drug affinity complex, which covalently binds circulating serum albumin. Albumin's long half-life dramatically extends the analog's circulating duration, producing sustained elevation of growth hormone and IGF-1 rather than the discrete pulses characteristic of native GHRH signaling. This distinction is scientifically important: the somatotropic axis evolved as a pulsatile system, and continuous versus pulsatile exposure is reported to produce different downstream effects on hepatic IGF-1 output and target tissue responsiveness. The DAC variant therefore functions as a research tool for deliberately investigating that difference. Laboratory applications include sustained-exposure endocrine protocols, IGF-1 response profiling, receptor desensitization studies, and comparative pharmacokinetics against the No DAC variant.

Common Research Areas

• Growth hormone axis research
• GHRH receptor pharmacology
• IGF-1 signaling studies
• Pharmacokinetic research
• Receptor desensitization studies
• Endocrine pulsatility profiling

Key Features

• Presentation: Lyophilized vial at 5 mg
• Category: Growth Hormone & Performance — wholesale supply only
• Minimum order quantity: 10 units per SKU
• Applied in growth hormone axis research and ghrh receptor pharmacology
• Cold-chain handling: store at 2–8°C, protected from light
• Research Use Only — not for human or animal consumption

Product Information

Category

Growth Hormone & Performance

Format

Lyophilized vial

Strength

5 mg

Minimum Order Quantity

10 units

Wholesale Availability

Wholesale only

Why Researchers Choose This Product

The DAC modification makes this the reference compound for studying sustained versus pulsatile GH signaling — a question central to somatotropic biology. Its extended half-life also reduces administration frequency in longer preclinical protocols.

Storage

Store lyophilized vials refrigerated at 2–8°C. Protect from heat and light. Reconstituted material should be kept refrigerated and handled under aseptic laboratory conditions. For laboratory research use only.

Frequently Asked Questions

What is CJC-1295 with DAC 5mg studied for?

CJC-1295 with DAC is a long-acting GHRH analog incorporating a drug affinity complex that binds serum albumin. It is studied for sustained somatotroph stimulation and for comparing continuous versus pulsatile growth hormone signaling. The albumin-binding modification produces sustained rather than pulsatile exposure, making it the reference tool for investigating how signaling pattern alters downstream IGF-1 output.

What research applications does CJC-1295 with DAC 5mg support?

Reported laboratory applications span growth hormone axis research, ghrh receptor pharmacology, igf-1 signaling studies, pharmacokinetic research, receptor desensitization studies, and endocrine pulsatility profiling. The DAC modification makes this the reference compound for studying sustained versus pulsatile GH signaling — a question central to somatotropic biology. Its extended half-life also reduces administration frequency in longer preclinical protocols.

What format, strength, and minimum order apply?

CJC-1295 with DAC 5mg is supplied as lyophilized vial at 5 mg. The minimum order quantity is 10 units per SKU, and it is available to wholesale buyers only — laboratories, research organizations, distributors, and qualified commercial accounts.

How should this product be stored and handled?

Store lyophilized vials refrigerated at 2–8°C. Protect from heat and light. Reconstituted material should be kept refrigerated and handled under aseptic laboratory conditions. For laboratory research use only.

Is this product suitable for human or animal use?

No. This product is supplied strictly for laboratory and scientific research by qualified professionals. It is not for human or animal consumption, is not intended for human or veterinary use, and is not approved to diagnose, treat, cure, or prevent any disease.

This product is intended exclusively for laboratory research and analytical purposes. NOT FOR HUMAN CONSUMPTION. Not intended to diagnose, treat, cure, or prevent any disease.